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(3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
(3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol is a synthetic small molecule belonging to the benzenesulfonamide class, characterized by a sulfonamide group S-linked to a benzene ring. It is an experimental compound and not approved for clinical use. The primary known molecular target of this compound is disintegrin and metalloproteinase domain-containing protein 17 (ADAM17), also known as tumor necrosis factor-alpha converting enzyme (TACE). ADAM17 plays a role in the proteolytic release of cell-surface proteins, including cytokines and growth factors, making it relevant in inflammation and cancer biology. No clinical indications or approved uses are reported for this molecule.[1][2][4]
- Other names
- (3S)-1-{[4-(2-butyn-1-yloxy)phenyl]sulfonyl}-3-pyrrolidinethiol1-{[4-(2-butyn-1-yloxy)phenyl]sulfonyl}-3-pyrrolidinethiol(3S)-1-[4-(but-2-yn-1-yloxy)benzenesulfonyl]pyrrolidine-3-thiol
02
Targets
ADAM17 (A disintegrin and metalloprotease 17)
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